Association of the HLA-DQA1 and HLA-DQB1 Alleles in Type 2 Diabetes Mellitus and Diabetic Nephropathy in the Han Ethnicity of China

Table 5

Frequency of HLA-DQA1 alleles in T2DM patients with and without DN.

HLA-DQA1 alleles	DN0 (𝑛=100)		DN1 (𝑛=210)
	PN	AF	PN	AF	𝜒^2	𝑃
DQA1*0101	16	0.080	34	0.081	0.002	0.968
DQA1*0102	21	0.105	44	0.105	2.862	0.091
DQA1*0103	19	0.095	43	0.102	0.082	0.775
DQA1*0104	11	0.055	39	0.093	2.619	0.106
DQA1*0201	12	0.060	31	0.074	0.400	0.527
DQA1*0301	27	0.135	69	0.164	0.888	0.346
DQA1*0302	27	0.135	29	0.069	7.172	0.007^(*)
DQA1*0401	10	0.050	36	0.086	2.516	0.113
DQA1*0501	38	0.190	65	0.155	1.214	0.270
DQA1*0601	19	0.095	30	0.071	1.034	0.309

PN: positive number; AF: antigen frequency; DN0: without DN group; DN1: DN group; ^(∗)𝑃 value < 0.05.