Clinical Study

Advanced Diabetic Nephropathy with Nephrotic Range Proteinuria: A Pilot Study of the Long-Term Efficacy of Subcutaneous ACTH Gel on Proteinuria, Progression of CKD, and Urinary Levels of VEGF and MCP-1

Figure 5

The change in urinary VEGF levels among the total group, complete and partial responders, and nonresponders. Urinary VEGF was significantly increased in patients demonstrating complete or partial reduction in urinary protein. (b) The change in urinary MCP-1 levels among the total group, complete and partial responders, and nonresponders. Urinary MCP-1 was unchanged by ACTH therapy.
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(a)
489869.fig.005b
(b)