Angiogenic and Vasculogenic Factors in the Vitreous from Patients with Proliferative Diabetic Retinopathy

Table 2

Comparisons of mean angiogenic and vasculogenic factor levels in proliferative diabetic retinopathy (PDR) patients with or without active neovascularization.

Disease group	VEGF (pg/mL)	sVEGFR-2 (pg/mL)	SCF (pg/mL)	s-kit (pg/mL)	PGE2  (pg/mL)
Active PDR	1099.9±1535.6	1692.5±1873.9	233.7±626.8	697.4±1528.1	28.2±11.1
Inactive PDR	150.7±237.7	1050.1±403.2	88.6±66.2	205.3±106.4	30.0±10.1
Controls	31.6±37.9	678.0±471.5	21.6±38.5	87.5±91.5	58.0±18.8
ANOVA 𝑃 value	<0.001*	0.007*	0.001*	<0.001*	<0.001*

∗Statistically significant at 5% level.
VEGF: vascular endothelial growth factor; sVEGFR-2: soluble vascular endothelial growth factor receptor-2; SCF: stem cell factor; s-kit: soluble c-kit; PGE₂: prostaglandin E₂.