Angiogenic and Vasculogenic Factors in the Vitreous from Patients with Proliferative Diabetic Retinopathy

Table 4

Relationship between angiogenic and vasculogenic factors and systemic disease variables.

Variable	VEGF (pg/mL)	sVEGFR-2 (pg/mL)	SCF (pg/mL)	s-kit (pg/mL)	PGE2  (pg/mL)
Type of diabetes
Insulin-dependent	1125.4±1819.4	1594.0±1950.7	209.9±614.4	601.3±1502.7	29.6±10.6
Noninsulin-dependent	472.9±507.9	1338.2±569.3	116.5±75.5	320.3±182.6	28.8±11.1
𝑃 value	0.611	0.698	0.118	0.578	0.972
Fasting blood glucose
Controlled	1296.1±1115.8	2133.0±2601.7	313.4±809.2	867.0±2014.4	31.0±11.0
Uncontrolled	912.9±1815.2	1158.1±504.8	906±74.2	297.9±177.0	28.4±10.5
𝑃 value	0.081	0.375	0.846	0.649	0.733
Hypertension
Yes	1117.3±1757.7	1639.4±1873.0	209.4±573.0	548.0±1358.0	29.4±10.6
No	672.6±1063.8	1008.8±535.1	59.7±28.0	330.6±196.2	29.2±12.5
𝑃-value	0.374	0.409	0.422	0.716	0.804

VEGF: vascular endothelial growth factor; sVEGFR-2: soluble vascular endothelial growth factor receptor-2; SCF: stem cell factor; s-kit: soluble c-kit; PGE₂: prostaglandin E₂.