Research Article
The Effect of Diabetes-Associated Autoantigens on Cell Processes in Human PBMCs and Their Relevance to Autoimmune Diabetes Development
| | Study group | No. of individuals | Age (years)
median, range | Age
(years) | Sex
(F/M) |
| | T1D recent onset | 12 | 12; 3–41 | 12
12
3
17
12
8
7
41
19
15
7
7 | M
M
F
M
F
F
M
M
M
F
F
F |
| First-degree relatives
autoantibodies negative
| 9 | 19; 5–52 | 5
7
32
52
43
19
22
16
8 | F
F
F
M
F
F
M
M
F |
| First-degree relatives
autoantibodies positive
| 9 | 7; 3–21 | 7
13
10
7
3
7
7
21
7 | F
F
M
F
M
F
F
F
F |
| | Controls | 13 | 27; 14–42 | 14
36
22
22
21
21
27
31
27
42
27
32
24 | M
F
F
F
F
M
F
M
M
M
F
F
M |
|
|
