Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice

Figure 4

Islet destruction and lymphocytic infiltration in nondiabetic NOD mice subject to construction stress. The number of islets per pancreatic section was scored as exemplified by the histology sections presented (scale 200 μm). At least three mice per group were included except for the diabetic NOD/LtJ-HMR mice during construction, which included only two mice. Note that there are no nondiabetic mice from the NOD/LtJ-HMR mice born after construction.