737485.fig.004
Figure 4: TRAV and TRBV polymorphic positions shown on a TCR/pMHC complex structure. Polymorphic positions are red, TCRα is light blue, TCRβ is blue, peptide is magenta, and MHC is green. Structure shown is HA1.7 TCR/HA peptide/HLA-DR4 (Protein Data Bank [43] ID 1J8H). The figure was generated using PyMOL (http://www.pymol.org/).