Research Article
The Missing Heritability in T1D and Potential New Targets for Prevention
Table 2
Previously identified polymorphisms in TRAV/TRBV genes near the pMHC interface.
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Region of the TCR variable domain tertiary structure. CDRs are as defined by Lefranc et al. [54], with CDR2 extended by one residue at the N-terminus to account for pMHC contacts with this position. 2From IMGT [55], as well as additional data from Mackelprang et al. [56] (in bold italics). IMGT TCR residue numbering used. |