Porcine Models of Accelerated Coronary Atherosclerosis: Role of Diabetes Mellitus and Hypercholesterolemia

Figure 3

Photomicrograph of a high-grade coronary atherosclerotic lesion obtained from a 13-month PCSK9 gain-of-function mutant pig fed a high cholesterol diet. C: calcifications; L: lumen; NC: necrotic core; Photomicrograph kindly provided by Dr. Erling Falk.