Table 4: Comparison of biochemical parameters in newly diagnosed type 2 diabetes before and after treatment with nateglinide.

GroupBefore taking nateglinideAfter taking nateglinideDifference in levels before and after nateglinide treatmentP values

Number of patients (M/F)32 (19/13)32 (19/13)
Weight .805
FPG .001*
PPG .001
DPG .001
HbA1C (%) .001*
GA (%) .001
TC .062*
TG .063*
LDL-C .002
HDL-C .252*
HOMA-IRI .008
HOMA-β .072
ALT .044*
AST .003*
CRE .451*
UA .869*

FPG: fasting plasma glucose; PPG: postprandial plasma glucose; DPG: diphosphoglycerate plasma glucose; HbA1C: glycosylated haemoglobin; GA: glycated albumin; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; HOMA-IRI: Homeostasis model method of assessment (HOMA) insulin resistance index; HOMA-β: HOMA β-cell function; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CRE: creatinine; UA: uric acid.
*Using nonparametric analysis method.