Structural Changes in Individual Retinal Layers in Diabetic Macular Edema
Figure 3
Characteristics of cystoid spaces in DME. ((a), (b)) Early-phase FA shows an enlarged foveal avascular zone and surrounding microaneurysms (arrowheads). (c) A late-phase image shows fluorescein pooling at the fovea. (d) Cystoid spaces (arrows) are accompanied by microaneurysms (arrowhead). (e) A late-phase FA image shows petalloid- (e) or honeycomb-pattern (f) fluorescein pooling, which is considered to correspond to cystoid spaces in OPL (arrow) or INL (arrowhead), respectively, on OCT image. Foveal cystoid spaces (arrowheads) have higher OCT reflectivity and its heterogeneity (g) or lower and homogeneous reflectivity (h).
