Notch Signaling Molecules Activate TGF-β in Rat Mesangial Cells under High Glucose Conditions

Figure 10

The expression of FN and TFG-𝛽 after intervention with DAPT determined using PCR for 12 hr. (a) RT-PCR strip chart for FN and TFG-𝛽. (b) The gray graph shows the relative statistical values for FN and TFG-𝛽 in each group. Compared with the NC group, the expression of the FN and TFG-𝛽 mRNA was significantly increased in the HG2 group. After DAPT intervention, the mRNA expression of FN and TFG-𝛽 decreased. ^▴𝑃 <0.05 versus NC group; ^•𝑃<0.05 versus HG2 group.

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