Notch Signaling Molecules Activate TGF-β in Rat Mesangial Cells under High Glucose Conditions
Figure 3
The expression of Notch pathway components in GMCs induced by 25 mmol/L glucose at various times determined using Western blot. (a) Western Blot strip chart for different times. At the 24 h time point, all Notch-related proteins were significantly enhanced. Notch1 protein was increased at both the 12 h and 24 h time points, with the 24 h increase being more pronounced. (b) The gray value statistics graph of the protein level. ▴ versus NC group; • versus 12 h group; ▪ versus 24 h group.
