Notch Signaling Molecules Activate TGF-<i>β</i> in Rat Mesangial Cells under High Glucose Conditions

<table>The expression of Smad4 after intervention with DAPT determined using western blot for 24 hr. (a) Western blot strip chart. (b) The gray graph shows the relative statistical values for Smad4 in each group. Compared with the NC group, the expression of the Smad4  protein was significantly increased in the HG2 group. After DAPT intervention, the protein expression of Smad4 decreased. <sup>▴</sup><svg height="11.375" id="M57" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus NC group; <sup>•</sup><svg height="11.375" id="M58" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus HG2 group.</table>

Journal of Diabetes Research

fig9

Figure 9

Figure 9: Notch Signaling Molecules Activate TGF-<i>β</i> in Rat Mesangial Cells under High Glucose Conditions 

Journal of Diabetes Research

Notch Signaling Molecules Activate TGF-β in Rat Mesangial Cells under High Glucose Conditions

Figure 9