Phenotypic Characterization of LEA Rat: A New Rat Model of Nonobese Type 2 Diabetes

Figure 2

Blood glucose levels after glucose loading in male LEA (𝑛=11, open circle) and Wistar rats (𝑛=5, closed circle) at 2 months of age (a), in male LEA (𝑛=12, open circle) and male Wistar rats (𝑛=4, closed circle) at 6 months of age (b), in male LEA (𝑛=13, open circle) and Wistar rats (𝑛=3, closed circle) at 12 months of age (c), in male LEA (𝑛=15, open circle) and Wistar rats (𝑛=3, closed circle) at 14 months of age (d). Plasma insulin levels after glucose loading in male LEA (𝑛=3, open circle) and Wistar rats (𝑛=4, closed circle) at 2 months of age (e), in male LEA (𝑛=5, open circle) and Wistar rats (𝑛=3, closed circle) at 12 months of age (f). Each value is expressed as the mean ± SD. *𝑃<0.05. **𝑃<0.01.

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