Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

Figure 1

Blood glucose and plasma gelsolin (pGSN) levels in nondiabetic and diabetic human volunteers (a) and mice (b) have been plotted here. The right panels show the correlation between the pGSN values and glycated hemoglobin (HbA1c) percentages in the blood samples. Inset boxes show the parameters obtained upon sigmoidal fit. The results are expressed as mean ± S.E.M. values are as mentioned in Methods (Section 2.8).

(a) Human

(b) Mice