Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin

Figure 3

(a) Blood glucose levels on day 0 and day 7 in high fat diet and Streptozotocin induced (HFD/STZ) C57BL/6 diabetic mice treated with daily doses of PBS, rhuGSN, and 28–161 have been plotted here. (b) Variation in measured fasting blood glucose values and pGSN levels in diabetic mice () before and after daily treatment with antihyperglycemic drug for two weeks has been plotted here. values are as mentioned in Methods (Section 2.8).

(a)

(b)