Data Mining for Identifying Novel Associations and Temporal Relationships with Charcot Foot

Figure 1

Association diagram showing the clinical milieu in which Charcot foot (pink node in center of square) often exists. Each node represents an ICD-9 code, with the size of the node proportional to its frequency in the overall dataset and node colors representing high-level clinical categories (see legend). Edges between nodes represent highly significant associations. Arrowheads show temporality with preceding nodes pointing to subsequent nodes. This figure was made using the following criteria: association 𝑃 value < 1.0 × 10⁻¹⁷⁶; association odds ratio > 200; temporal 𝑃 value < 1.0 × 10⁻⁶. The two red nodes directly pointing to Charcot foot are related to type 2 diabetes (ICD-9 codes 250.60 and 250.90).