Research Article
Effects of Unilateral Nephrectomy on Renal Function in Male Spontaneously Diabetic Torii Fatty Rats: A Novel Obese Type 2 Diabetic Model
Table 1
Histopathological findings of kidney in sham group and 1/2 Nx group.
| Findings | | Group | | 1/2 Nx | | Sham | Animal number | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | | 9 | 10 | 11 | 12 | 13 |
| Glomerulus | | | | | | | | | | | | | | | | Glomerulosclerosis | | + | + | 2+ | + | + | 2+ | + | + | | ± | ± | ± | ± | − | Tubule | | | | | | | | | | | | | | | | Regeneration | | + | 2+ | 2+ | 2+ | 2+ | 2+ | 2+ | 2+ | | + | + | + | + | + | Dilatation | | 2+ | 2+ | + | 2+ | + | 2+ | 2+ | 2+ | | + | + | ± | + | + | Hyaline cast | | + | + | ± | ± | + | ± | + | + | | + | + | ± | + | ± | Deposit, hyaline droplet | | ± | − | − | − | − | − | − | − | | − | − | − | − | − | Armanni-Ebstein change | | + | + | + | + | + | ± | ± | − | | + | + | + | + | + | Mineralization | | − | + | + | + | ± | + | + | + | | + | + | + | − | + | Interstitial | | | | | | | | | | | | | | | | Fibrosis, interstitial | | − | + | − | − | − | + | − | + | | − | + | ± | − | ± | Infiltration, inflammatory cell, interstitial | | + | + | 2+ | 2+ | + | 2+ | 2+ | 2+ | | ± | − | + | ± | + |
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−: negative; ±: very slight; +: slight; 2+: moderate; 3+: severe.
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