Research Article
Low Molecular Weight Fucoidan Alleviates Cardiac Dysfunction in Diabetic Goto-Kakizaki Rats by Reducing Oxidative Stress and Cardiomyocyte Apoptosis
Figure 1
Influence of LMWF administration on myocardial contractility of diabetic GK rats determined in isolated perfused hearts. Peak left ventricular pressure (LVP) was shown in (a). Left ventricular developed pressures (LVDP) at both baseline levels and stimulated by isoprenaline (ISO, 10−5 M) were shown in (b). The maximum rates of contraction and relaxation of myocardium (±dp/dt) at both baseline levels and in response to ISO stimulation were shown in ((c), (d)). = 5–7 for each group, , , versus control group; versus DM group.
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