Cardiomyopathy in Offspring of Pregestational Diabetic Mouse Pregnancy

Figure 1

Histological images of six-week-old offspring of type 1 diabetic mouse demonstrating the application of the Aperio software. (a) Full image taken with Aperio digital scanning microscope. LV: left ventricle wall; RV: right ventricle wall; IVS: interventricular septum. (b) Mark-up image showing the detection of collagen by the Aperio positive pixel count algorithm. Blue represents negative background and yellow/orange represents positive collagen detection, as shown in corresponding 40x magnified images.