[Retracted] Hyperglycemia Induces Toll-Like Receptor-2 and -4 Expression and Activity in Human Microvascular Retinal Endothelial Cells: Implications for Diabetic Retinopathy

Figure 8

siRNA for TLR-2 and TLR-4 attenuates downstream inflammatory biomediators: HMVRECs treated with 0.75 g siRNA for 18–24 hours in transfection media. The cells were replaced in complete media and allowed to settle for 24 hours. Subsequently cells were serum starved for 2 hours and HG treatments given as described in Figure 1. (a) NF-B, (b) TNF-, and (c) IL-8. versus control and versus 25 mM; Sc: scrambled sense RNA.

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