Beneficial Effects of Adiponectin on Periodontal Ligament Cells under Normal and Regenerative Conditions
Figure 1
Effects of EMD and/or adiponectin (1 μg/mL) on the mRNA expression of TGFβ1, VEGF, POSTN, and RUNX2 at 1 d (a) and 3 d (b). Untreated cells were used as control. Mean ± SEM (); *significant () difference between groups. Effects of various concentrations of adiponectin (0.3, 1, and 3 μg/mL) on the mRNA expression of TGFβ1 and VEGF in the absence (c) and presence (d) of EMD at 1 d. Mean ± SEM (). Effects of EMD and/or adiponectin (1 μg/mL) on TGFβ1 (e) and VEGF (f) protein levels at 3 d. Unstimulated cells were used as control. Mean ± SEM (); *significant () difference between groups. Effects of adiponectin (1 μg/mL) on the IL-6, IL-8, TNFα, and COX2 mRNA expressions at 1 d (g). Unstimulated cells were used as control. Mean ± SEM (); *significantly () different from control.
