Beneficial Effects of Adiponectin on Periodontal Ligament Cells under Normal and Regenerative Conditions
Figure 3
Effects of F. nucleatum (Fn), A. actinomycetemcomitans (Aa), P. gingivalis (Pg), and T. denticola (Td) (all OD: 0.1) on the mRNA expression of adiponectin in PDL cells at 1 d (a). Untreated cells were used as control. Mean ± SEM (); *significantly () different from control. Effect of P. gingivalis (Pg; OD: 0.1) on the adiponectin protein level in medium from PDL cells at 1 d and 2 d (b). Untreated cells were used as control. Mean ± SEM (); *significant () difference between groups. Effects of P. gingivalis (OD: 0.1) on the mRNA expression of adiponectin receptors (AdipoR1 and AdipoR2) at 1 d and 3 d (c). Untreated cells were used as control. Mean ± SEM (); *significantly () different from control. Effects of adiponectin (1 μg/mL) on its own mRNA expression (d) and the expression of its receptors AdipoR1 and AdipoR2 (e) at 1 d. Untreated cells served as control. Mean ± SEM (); *significant () difference between groups.