Research Article
Vitamin Status as a Determinant of Serum Homocysteine Concentration in Type 2 Diabetic Retinopathy
Table 1
Demographic and laboratory characteristics of patients with type 2 diabetes mellitus.
| | Characteristics | DR− () | DR+ () | value |
| | Age (years) | 61.0 (55.0–67.0) | 68.0 (60.0–75.0) | 0.001 | | Positive family history (%) | 54.7 () | 86.2 () | <0.001 | | BMI (kg/m²) | 27.8 (26.1–30.2) | 29.2 (27.9–31.2) | 0.004 | | Diabetes duration (years) | 6.0 (3.0–9.0) | 15.0 (10.0–22.0) | <0.001 | | Fasting serum glucose (mg/dL) | 119.0 (103.0–136.0) | 154.0 (126.0–188.0) | <0.001 | | HbA1C (%) | 6.7 (6.0–7.6) | 7.4 (6.6–8.9) | <0.001 | | Serum creatinine (mg/dL) | 0.9 (0.7–1.0) | 0.9 (0.8–1.1) | 0.024 | | Serum homocysteine (μmol/L) | 11.1 (9.5–13.6) | 16.3 (14.7–19.8) | <0.001 | | Hyperhomocysteinemia (%) | 14.7 () | 70.8 () | <0.001 | | Serum folic acid (ng/mL) | 11.0 (8.3–17.0) | 8.7 (7.2–10.3) | <0.001 | | Serum vitamin B2 (μg/L) | 10.8 (7.8–13.2) | 9.1 (7.0–12.7) | 0.179 | | Serum vitamin B6 (μg/L) | 11.6 (9.9–13.2) | 11.0 (8.0–14.6) | 0.481 | | Serum vitamin B12 (pg/mL) | 361.5 (255.6–471.2) | 288.8 (209.5–416.5) | 0.014 | | Systolic blood pressure (mmHg) | 125.0 (115.0–130.0) | 130.0 (120.0–135.0) | 0.016 | | Diastolic blood Pressure (mmHg) | 75.0 (70.0–80.0) | 75.0 (70.0–80.0) | 0.409 |
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Values are presented as median (interquartile range) or % (number).
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