Association of Serum Vaspin and Adiponectin Levels with Renal Function in Patients with or without Type 2 Diabetes Mellitus

Table 1

Baseline of all subjects divided by T2DM and RI.

	Non-T2DM			T2DM
	RI	Non-RI	𝑃 value	RI	Non-RI	𝑃 value
Gender (male : female)	9 : 18	151 : 69		13 : 10	75 : 71
Age (years)	73.85±9.02	53.19±17.13	<0.001*	75.70±7.38	61.03±10.50	<0.001*
BMI (kg/m^2)	22.01±2.51	24.17±3.71	<0.01*	22.90±3.17	25.56±4.49	<0.01*
SBP (mmHg)	149.70±26.89	135.05±24.13	<0.01*	147.78±21.92	136.92±19.80	<0.05*
DBP (mmHg)	82.00±10.47	78.64±13.33	0.227	79.96±11.98	79.59±11.17	0.886
Vaspin (ng/mL)	0.55 (0.43–1.14)	0.52 (0.23–1.32)	0.402	0.50 (0.29–0.91)	0.38 (0.23–0.74)	0.245
Adiponectin (ng/mL)	16082.44±9926.20	7824.135±7032.657	<0.01*	12987.34±14623.76	8744.92±5628.95	0.349
hsCRP (mg/L)	3.27 (3.10–3.27)	3.34 (2.93–7.05)	0.266	1.85 (0.05–6.21)	1.01 (0.06–3.06)	0.428
Crcl (mL/min)	48.01±10.43	95.94±36.92	<0.001*	46.24±10.45	112.58±43.43	<0.001*
Cr (𝜇mol/L)	92.48±28.11	73.84±16.29	<0.01*	100.04±26.65	59.68±16.78	<0.001*
BUN (mmol/L)	6.26±2.36	5.37±1.36	0.068	8.46±3.75	5.61±1.69	<0.01*
UA (𝜇mol/L)	392.41±80.61	339.41±85.37	<0.01*	388.96±96.66	288.86±81.32	<0.001*
FBG (mmol/L)	4.96±0.63	5.05±0.74	0.576	7.40±2.41	7.91±2.95	0.498
PG2h (mmol/L)	7.11±2.02	7.14±2.32	0.974	12.06±3.58	12.53±4.41	0.732
HbA1c (%)	5.13±1.75	5.66±0.40	0.342	8.86±1.81	8.66±2.10	0.709
TC (mmol/L)	4.89±1.05	4.48±1.25	0.124	4.40±1.07	4.69±1.07	0.242
TG (mmol/L)	1.41±0.64	1.45±0.83	0.797	1.32 (0.99–1.63)	1.51 (1.09–2.53)	0.131
HDL-C (mmol/L)	1.30±0.36	1.18±0.30	0.107	1.13±0.42	1.20±0.33	0.387
LDL-C (mmol/L)	2.80±0.85	2.59±0.99	0.326	2.62±1.05	2.71±0.72	0.627
ApoA (g/L)	1.32±0.16	1.26±0.15	0.314	1.29±0.26	1.31±0.25	0.738
ApoB (g/L)	0.90±0.17	1.12±0.81	0.350	0.87 (0.70–1.02)	0.96 (0.77–1.22)	0.170
LPA (mg/L)	169.25±74.190	174.46±106.72	0.877	5.55 (2.80–53.00)	5.90 (1.14–19.83)	0.229
FIB (g/L)	2.56±0.51	2.37±0.65	0.206	2.78±0.64	3.09±0.83	0.132

The data are presented as the number, mean ± S.D., or median (interquartile range); ^∗𝑃<0.05.
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; vaspin: visceral adipose-tissue-derived serpin; hsCRP: high-sensitive C-reactive protein; Crcl: creatinine clearance; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; FBG: fasting blood glucose; PG2h: 2-hour postprandial glucose; HbA1c: hemoglobin A1c; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ApoA: apolipoprotein A; ApoB: apolipoprotein B; LPA: lipoprotein A; FIB: fibrinogen.