Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors-γ2 with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status in Emirati Population

Table 3

Genotype and allele frequency distribution of rs10885409 of TCF7L2 and PPAR- P12A mutation without obesity consideration.

	Total	T2DM patients; (%)	Nondiabetic subjects; (%)	value
TCF7L2 genotypes
TT	111	61 (22.5)	50 (23.3)	NS
CT	221	121 (44.6)	100 (46.5)	NS
CC	154	89 (32.9)	65 (30.2)	NS
Allele frequencies
T	443	243 (0.45)	205 (0.48)	NS
C	529	299 (0.55)	225 (0.52)	NS
PPAR- genotypes
CC	447	250 (91.9)	197 (91.2)	NS
CG	41	22 (8.1)	19 (8.8)	NS
GG	0	0	0	NS
Allele frequencies
C	935	522 (0.96)	413 (0.96)	NS
G	41	22 (0.04)	19 (0.04)	NS