Association of the Genetic Polymorphisms in Transcription Factor 7-Like 2 and Peroxisome Proliferator-Activated Receptors-γ2 with Type 2 Diabetes Mellitus and Its Interaction with Obesity Status in Emirati Population

Table 7

Biochemical parameters in different TCF7L2 rs10885409 genotypes in nonobese Emirati T2DM cases and controls.

Genotypes

Cholesterol (mmol/L)

P

LDL (mmol/L)

P

HDL (mmol/L)

P

TGS (mmol/L)

P

HB1Ac (mmol/L)

P

T2DM

Nondiabetics

T2DM

Nondiabetics

T2DM

Nondiabetics

T2DM

Nondiabetics

T2DM

Nondiabetics

CC

4.12 ± 1.0

4.56 ± 0.68

0.1805

2.28 ± 0.94

2.57 ± 0.81

0.2700

1.3 ± 0.39

1.28 ± 0.39

0.8597

1.34 ± 0.84

1.37 ± 1.26

0.9157

7.62 ± 1.87

5.48 ± 0.44

0.0003

CT + TT

4.05 ± 0.83

4.55 ± 1.13

0.0175

3.86 ± 0.76

2.55 ± 0.98

0.0001

1.28 ± 0.84

1.42 ± 0.71

0.4050

1.4 ± 0.81

1.04 ± 0.44

0.0221

7.64 ± 1.96

5.76 ± 0.73

0.0001

P values

0.7565

0.9718

0.0001

0.9393

0.8946

0.4379

0.7375

0.1755

0.9611

0.2302