Association of ATP-Binding Cassette Transporter A1 Gene Polymorphisms in Type 2 Diabetes Mellitus among Malaysians

Table 2

Genotypic and allelic frequencies of R219K, C69T, and R230C, respectively, according to subjects.

		T2DM (%)	(95% CI)	Controls (%)	value
R219K	GG	94 (57.3%)		56 (33.9%)
Genotypes and alleles	GA	55 (33.5%)		77 (46.6%)	0.00
	AA	15 (9.1%)		32 (19.3%)
Alleles	G	243 (74%)		189 (57.2%)	0.00
	A	85 (26%)		141 (42.8%)
	GG versus GA		0.07–0.34		0.00
Post hoc test	GG versus AA		0.11–0.49		0.00
	GA versus AA		−0.09–0.29		0.467
C69T	CC	65 (39.6%)		83 (50.3%)
Genotypes and alleles	CT	48 (29.2%)		48 (29%)	NS
	TT	51 (31%)		34 (20.6%)
	C	154 (54.2%)		190 (64.8%)	0.00
Alleles	T	150 (45.8%)		116 (35.2%)
	CC versus CT		−0.18–0.06		0.352
Post hoc test	CC versus TT		−0.29–−0.02		0.01
	CT versus TT		−0.24–0.04		0.179
R230C	CC	69 (42%)		64 (38.7%)
Genotypes and alleles	CT	72 (43.6%)		67 (40.6%)	NS
	TT	32 (19.3%)		34 (20.6%)
	C	210 (63.9%)		195 (59%)	0.695
Alleles	T	136 (36.1%)		135 (41%)
	CC versus CT		0.11-0.12		0.989
Post hoc test	CC versus TT		−0.04–0.27		0.147
	CT versus TT		−0.04–0.26		0.147

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