Association of ATP-Binding Cassette Transporter A1 Gene Polymorphisms in Type 2 Diabetes Mellitus among Malaysians

Table 6

Conflicting results of genetic variants found in different populations.

Gene variants	Diseases	Populations	References	Number of subjects	value
ABCA1 R1587K	CAD	Chinese	Guo et al., 2011 [9]	222	NS
ABCA1 R219K	CHD	Turkish	Çoban et al., 2014 [10]	627	NS
ABCA1 C69T	CAD	Turkish	Ergen et al., 2008 [11]	127	NS
ABCA1 R219K	CHD	Spanish	Cenarro et al., 2003 [12]	216	S
ABCA1 C69T	T2DM	Saudi Arabian	Alharbi et al., 2013 [13]	756	S
ABCA1 C69T	T2DM	Turkish	Ergen et al., 2012 [8]	157	S
ABCA1 R219K, R1587K, C69T	T2DM	French	Porchay-Baldérelli et al., 2009 [14]	482	NS
ABCA1 R230C	CAD	Mexican	Villarreal-Molina et al., 2012 [15]	2193	S
ABCA1 R219K	Overweight/obese	Thai	Kitjaroentham et al., 2007 [16]	229	NS
ABCA1 R219K, R1587K, C69T	Ischemic stroke	English	Pasdar et al., 2007 [17]	887	S
ABCA1 R1219K	CAD	American	Benton et al., 2007 [18]	6814	NS
R219K	T2DM	Malaysian	Current study	164	S

NS: nonsignificant (), S: significant ().