Sex-Differences in Renal Expression of Selected Transporters and Transcription Factors in Lean and Obese Zucker Spontaneously Hypertensive Fatty Rats

Figure 1

PAS staining in renal cortical slices. Renal sections of lean (le) and obese (ob) ZSF1 rats were stained with PAS and structural changes were analyzed. Examples for histological changes in renal tissue are marked as follows: #, tubular atrophy and dilatation; ##, hyaline protein casts in tubular lumen; §, pressure-induced deformation of glomerulus; §§, dilatation of Bowman’s capsule and protein cast in Bowman’s space; §§§, glomerulosclerosis. The arrows mark the thickening of tubular and glomerular basement membranes. Magnification: 200x. Representative images from three different rats under each condition are shown.