Sex-Differences in Renal Expression of Selected Transporters and Transcription Factors in Lean and Obese Zucker Spontaneously Hypertensive Fatty Rats

Figure 3

Influence of dicarboxylates, metabolites, and drugs on OAT2-mediated cGMP uptake in HEK293 cells. The uptake of cGMP was determined after 5 min incubation with 10 μM cGMP (0.1 μM cGMP + 9.9 μM unlabeled cGMP) alone (controls) or in the presence of 500 μM potential inhibitors at 37°C. (a) Dicarboxylates and metabolites; (b) drugs. Data are presented as mean ± SEM. . ; , compared to control.

(a)

(b)