The Genetic Profile from HLA and Non-HLA Loci Allows Identification of Atypical Type 2 Diabetes Patients

Table 2

Allelic frequencies of the SNPs: (a) type 1 diabetes, (b) type 2 diabetes, and (c) atypical diabetes.

(a)

Variant	Allelic frequencies		OR	CI	corrected
	Type 1 diabetes	Control
INS-VNTR
I	0.91	0.72	3.79	2.51–5.74	0.000
III	0.09	0.28
rs689
A	0.88	0.72	2.83	1.96–4.09	0.0000
T	0.12	0.28
rs3842753
A	0.86	0.72	2.44	1.72–3.47	0.0001
C	0.14	0.28

(b)

Variant	Allelic frequencies		OR	CI	corrected
	Type 2 diabetes	Control
INS-VNTR
I	0.75	0.72	1.28	0.94–1.72	0.11
III	0.25	0.28
rs689
A	0.67	0.72	0.81	0.60–1.07	0.14
T	0.33	0.28
rs3842753
A	0.68	0.72	0.84	0.63–1.12	0.26
C	0.32	0.28

(c)

Variant	Allelic frequencies		OR	CI	corrected
	Atypical diabetes	Control
INS-VNTR
I	0.82	0.72	1.75	1.13–2.71	0.01
III	0.18	0.28
rs689
A	0.79	0.72	1.51	1.51–2.25	0.04
T	0.21	0.28
rs3842753
A	0.74	0.72	1.23	0.84–1.79	0.31
C	0.24	0.28

OR: odds ratio; CI: confidence intervals.