Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes
Table 1
Profile of spontaneous hyperglycemia in individual ZDSD rats (6:00 a.m. fed BG levels, mg/dL).
Animal ID
7 weeks
9 weeks
11 weeks
13 weeks
15 weeks
17 weeks
19 weeks
21 weeks
23 weeks
25 weeks
27 weeks
29 weeks
31 weeks
1
121
130
133
149
140
112
163
230
270
375
472
487
527
2
111
130
120
133
124
129
113
129
172
234
407
487
505
3
139
146
128
158
123
138
136
237
296
341
406
443
494
4
133
125
124
137
133
160
133
313
367
405
482
537
531
6
134
127
116
151
144
140
140
172
180
324
456
463
483
7
140
131
133
146
158
197
153
438
472
502
535
523
531
8
114
131
106
131
125
147
198
301
378
408
489
495
545
9
122
144
119
152
160
292
395
394
514
541
535
593
564
10
131
154
120
162
169
265
322
404
490
451
496
592
524
11
133
123
140
168
326
405
442
511
555
544
545
536
592
12
112
123
118
141
147
207
247
411
446
461
501
566
621
13
129
138
134
146
148
265
366
453
438
507
600
502
572
14
141
143
128
157
171
199
325
386
447
493
509
540
514
15
133
126
128
134
141
278
365
436
507
544
578
526
584
16
114
135
129
148
148
178
142
97
210
322
473
427
465
17
118
117
108
138
135
149
132
169
144
371
472
457
483
18
140
123
116
133
153
176
219
140
235
121
393
391
515
19
129
131
115
141
139
158
287
363
423
451
525
511
549
20
107
142
126
188
162
107
284
379
416
463
487
541
531
21
124
141
112
143
108
114
138
189
410
424
458
472
511
22
136
129
140
133
116
120
128
225
231
295
427
454
457
23
123
129
125
138
159
132
113
124
221
180
233
303
407
24
146
131
116
140
118
207
286
397
508
494
525
575
635
Values are represented as different fonts as each animal becomes progressively hyperglycemic. Normal represents relatively normoglycemic, bold represents hyperglycemic (125–249 mg/dL), and italic represents diabetic and overtly diabetic (>250 mg/dL).