Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes

Table 1

Profile of spontaneous hyperglycemia in individual ZDSD rats (6:00 a.m. fed BG levels, mg/dL).

Animal; ID	7; weeks	9; weeks	11; weeks	13; weeks	15; weeks	17; weeks	19; weeks	21; weeks	23; weeks	25; weeks	27; weeks	29; weeks	31; weeks
1	121	130	133	149	140	112	163	230	270	375	472	487	527
2	111	130	120	133	124	129	113	129	172	234	407	487	505
3	139	146	128	158	123	138	136	237	296	341	406	443	494
4	133	125	124	137	133	160	133	313	367	405	482	537	531
6	134	127	116	151	144	140	140	172	180	324	456	463	483
7	140	131	133	146	158	197	153	438	472	502	535	523	531
8	114	131	106	131	125	147	198	301	378	408	489	495	545
9	122	144	119	152	160	292	395	394	514	541	535	593	564
10	131	154	120	162	169	265	322	404	490	451	496	592	524
11	133	123	140	168	326	405	442	511	555	544	545	536	592
12	112	123	118	141	147	207	247	411	446	461	501	566	621
13	129	138	134	146	148	265	366	453	438	507	600	502	572
14	141	143	128	157	171	199	325	386	447	493	509	540	514
15	133	126	128	134	141	278	365	436	507	544	578	526	584
16	114	135	129	148	148	178	142	97	210	322	473	427	465
17	118	117	108	138	135	149	132	169	144	371	472	457	483
18	140	123	116	133	153	176	219	140	235	121	393	391	515
19	129	131	115	141	139	158	287	363	423	451	525	511	549
20	107	142	126	188	162	107	284	379	416	463	487	541	531
21	124	141	112	143	108	114	138	189	410	424	458	472	511
22	136	129	140	133	116	120	128	225	231	295	427	454	457
23	123	129	125	138	159	132	113	124	221	180	233	303	407
24	146	131	116	140	118	207	286	397	508	494	525	575	635

Values are represented as different fonts as each animal becomes progressively hyperglycemic. Normal represents relatively normoglycemic, bold represents hyperglycemic (125–249 mg/dL), and italic represents diabetic and overtly diabetic (>250 mg/dL).