Ileal Interposition in Rats with Experimental Type 2 Like Diabetes Improves Glycemic Control Independently of Glucose Absorption

Figure 4

Effects of STZ treatment ((a), (b)) and IIP surgery ((c), (d)) on oral glucose tolerance ((a), (c)) and insulin tolerance ((b), (d)). Before surgery: oral glucose tolerance tests (OGTTs) in (a) and insulin tolerance tests (ITTs) in (b) were performed during the 12th week of life in 9 animals that did not receive STZ (HFD) and in 18 animals that were treated with STZ (HFD STZ). After surgery: OGTTs (c) and ITTs (d) were performed during the 15th week of life in STZ-treated animals that had been sham-operated (HFD STZ sham, 9 animals) and in STZ-treated animals that had been IIP-operated (HFD STZ IIP, 9 animals). Mean values ± SEM are indicated. , , and .

(a)

(b)

(c)

(d)