NADPH Oxidase-Induced NALP3 Inflammasome Activation Is Driven by Thioredoxin-Interacting Protein Which Contributes to Podocyte Injury in Hyperglycemia

Figure 3

In HG-stimulated podocytes the expression of is enhanced. (a) Western blotting gel document showing the expression of in cultured human podocytes without or with HG treatment for indicated time. (b) Summarized data of protein expression of in podocytes without or with stimulation of HG (). (c) Summarized data showing the effect of HG on NADPH activity in cultured human podocytes (). Data were presented as percent increases in ethidium fluorescence compared to Ctrl. (d) Summarized data showing the fold changes in production, which are normalized to Ctrl (). Ctrl: control; HG: high glucose. compared with Ctrl.

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