Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes

Figure 2

Logistic analysis of urinary concentrations of angiotensinogen normalized by urinary concentrations of creatinine (UAGTCR) before treatment. Good responders to the alogliptin treatment were defined in terms of % change in urinary concentrations of Alb normalized by urinary concentrations of creatinine less than −25% after the 12-week treatment, and a logistic analysis of UAGTCR before treatment showed the area under the curve as 0.644. When we set the cutoff value of UAGTCR as 20.8 μg/g Cr, the maximum specificity (17/27 = 63.0%) and sensitivity (10/16 = 62.5%) were obtained (Youden index = 0.255).

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