Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions

Figure 6

MTT assay (absorbance values) for cell proliferation for PNTA1 ((a), (b), and (c)), 22Rv1 ((d), (e), and (f)), and PC3 cells ((g), (h), and (i)) under normal conditions ((a), (d), and (g)), 1 day of preincubation with hyperglycemic medium ((b), (e), and (h)), 7 days of preincubation with hyperglycemic medium ((c), (f), and (i)), and treatment with DMSO, 500 μM, 5 mM, or 10 mM of MLT for 1 and 2 days. represents significant differences among the different concentrations of melatonin exposure for 1 day (parametric data). + represents significant differences among the different concentrations of melatonin exposure for 2 days (parametric data).

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(b)

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(d)

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(i)