Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions

Figure 7

Determination of cell cycle analysis by DNA content using flow cytometry. 22Rv1 ((a), (b), (c), and (d)), PNTA1 ((e), (f), (g), and (h)), and PC3 ((i), (j), (k), and (l)) cells maintained under normal conditions ((a), (e), and (i)), treated with MLT (5 mM or 10 mM) for 1 day ((b), (f), and (j)), incubated with HG medium for 2 days ((c), (g), and (k)), and preincubated with HG medium for 1 day and then exposed to MLT (5 mM or 10 mM) for an additional 1 day ((d), (h), and (l)). DNA fragmentation: white peaks; G0/G1: blue peaks; S: green areas; and G2/M: red peaks.

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