Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics

Figure 1

Schematic of plasma glucose ¹³C-isotopomer formation following infusion of [U-¹³C₆]glucose (represented by black closed circles), its initial conversion to [1,2,3-¹³C₃]pyruvate and lactate via glycolysis, and gluconeogenic conversion of this isotopomer to form M+2 and M+3 glucose isotopomers (shown in grey).