Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients

Figure 1

E-PASP is increased in DM and in Hp 2-2. (a) Association of e-PASP and DM. Among individuals with high e-PASP, the prevalence of DM was significantly increased ( compared to non-DM individuals). There was no relationship between DM and e-PASP in individuals with normal e-PASP. (b) Association of Hp phenotype and e-PASP. DM dependent significant differences in the prevalence of high e-PASP seen in (a) above were only in study participants with the Hp 2-2 phenotype ( comparing prevalence of high e-PASP in Hp 2-2 participants with and without DM).

(a)

(b)