Hypoglycemic Activity through a Novel Combination of Fruiting Body and Mycelia of Cordyceps militaris in High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice

Figure 5

Specific protein expression of skeletal muscle and adipose tissue. (a) The protein expression of insulin receptor substrate-1 (IRS-1), phosphorylated IRS-1 (pIRS-1), protein kinase B (AKT), phosphorylated AKT (pAKT), and glucose transporter type 4 (GLUT-4) in skeletal muscle was measured. β-actin was used as a loading control in Western blot analysis and the measurement was expressed as a ratio of specific protein/β-actin expression. (b) Analysis for IRS-1, pIRS-1, AKT, pAKT, GLUT-4, and peroxisome proliferator-activated receptor γ (PPAR-γ) in adipose tissue. Data is expressed as the means ± SEM of samples. Symbols specify significant difference from DM with and indicating and , respectively.