Use of Drosophila as an Evaluation Method Reveals imp as a Candidate Gene for Type 2 Diabetes in Rat Locus Niddm22

Figure 3

dilp2 and dilp3 expression are significantly reduced in the imp mutant larvae. q-PCR analysis was conducted to examine the dilp expression on the third instar larva in the fed state. dilp2 and dilp3, but not dilp5, were reduced to less than the half of the control strain. .