Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway

Figure 5

FLZ increases cytosolic ATP/ADP ratio at glucotoxicity. INS-1E cells were cultured at G11.1 or G30 for 3 days. Cells were treated without or with 10 μM FLZ. Data are mean ± S.E.M. of seven independent experiments. versus the value at G5.5; versus the value at G30 without FLZ.