In Vitro and In Vivo Effects of Metformin on Osteopontin Expression in Mice Adipose-Derived Multipotent Stromal Cells and Adipose Tissue

Figure 8

Expression of mRNA for OPN in experimental cultures. Quantification of relative values was performed using method, normalizing data to control culture and including expression of reference gene. Data are presented as the mean fold change of relative expression and compared to control cultures (normalized to 100%); error bars represent standard deviation from the mean calculated for normalized values obtained in three separate reactions; asterisks represent statistically significant differences ().