Inflammatory Cytokine Profile Associated with Metabolic Syndrome in Adult Patients with Type 1 Diabetes

Table 2

Inflammatory profile in total T1D population and in patients with and without MS.

Parameter	T1D population; ()	Patients with MS; ()	Patients without MS; ()
IL-8, pg/mL (median, IR)	18.2; (8.68–41.22)	24.6; (12.65–46.5)	13.4; (7.0–34.4)	0.064
IL-6, pg/mL (median, IR)	1.5; (1.5–3.2)	1.5; (1.5–4.7)	1.5	NS
IL-10, pg/mL (median, IR)	2.3; (2.3–3)	2.3; (2.3–4.4)	2.3	NS
TNF, pg/mL (median, IR)	2.7; (2.7–4.8)	2.7; (2.7–7.8)	2.7	NS
Adiponectin, pg/mL (median, IR)	9.4; (5.7–15.5)	8.9; (5.4–14.9)	9.4; (6.6–15.6)	NS
Resistin, pg/mL (median, IR)	1180.3; (775.8–1896.8)	1627.4; (838.8–2233.8)	1055; (631.8–1459.2)	0.010
%Patients with resistin >1108 pg/mL	55%	71%	44%	0.021

IR: interquartile range, T1D: type 1 diabetes, MS: metabolic syndrome, NS: not significant, IL-8: interleukin-8, IL-6: interleukin-6, IL-10: interleukin-10, and TNF: tumor necrosis factor. ^*Comparing patients with and without MS, using Mann-Whitney test.