Research Article

Exenatide Treatment Causes Suppression of Serum Ghrelin Levels following Mixed Meal Test in Obese Diabetic Women

Table 2

Serum glucose, insulin, and ghrelin levels before (0 minutes) and at 60, 120, and 180 minutes following mixed meal test with and without exenatide usage.

Time (minute)With exenatide (mean ± SD)Without exenatide (mean ± SD)

Glucose (mg/dL)0150.0 ± 22.1157.2 ± 19.7
60204.8 ± 42.0235.8 ± 28.2
120178.2 ± 38.4233.7 ± 27.5
180130.5 ± 24.3161.7 ± 27.9

Insulin (µg/mL)014.2 ± 3.9113.6 ± 3.1
6043.0 ± 13.849.9 ± 22.2
12068.8 ± 39.295.9 ± 42.5
18034.3 ± 15.544.6 ± 16.4

Ghrelin (pg/mL)0294.4 ± 57.5283.7 ± 74.0
60268.2 ± 52.2302.0 ± 97.3
120267.5 ± 63.3278.7 ± 84.0
180234.5 ± 59.4298.1 ± 53.1

SD: standard deviation. Significant change compared to baseline value after Bonferroni correction ().