Exenatide Treatment Causes Suppression of Serum Ghrelin Levels following Mixed Meal Test in Obese Diabetic Women
Table 2
Serum glucose, insulin, and ghrelin levels before (0 minutes) and at 60, 120, and 180 minutes following mixed meal test with and without exenatide usage.
Time (minute)
With exenatide (mean ± SD)
Without exenatide (mean ± SD)
Glucose (mg/dL)
0
150.0 ± 22.1
157.2 ± 19.7
60
204.8 ± 42.0
235.8 ± 28.2
120
178.2 ± 38.4
233.7 ± 27.5
180
130.5 ± 24.3
161.7 ± 27.9
Insulin (µg/mL)
0
14.2 ± 3.91
13.6 ± 3.1
60
43.0 ± 13.8
49.9 ± 22.2
120
68.8 ± 39.2
95.9 ± 42.5
180
34.3 ± 15.5
44.6 ± 16.4
Ghrelin (pg/mL)
0
294.4 ± 57.5
283.7 ± 74.0
60
268.2 ± 52.2
302.0 ± 97.3
120
267.5 ± 63.3
278.7 ± 84.0
180
234.5 ± 59.4
298.1 ± 53.1
SD: standard deviation. Significant change compared to baseline value after Bonferroni correction ().