Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets

Figure 7

(a) Immunofluorescent staining for glucagon (green color) and DAPI (white color) in human islet grafts from PSN632408- and vehicle-treated mice with normoglycaemia at 4 weeks after transplantation. (b) Percentage of α-cell area in human islet grafts. The α-cell area in PSN632408-treated mice () was significantly increased compared with vehicle-treated mice () ().

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(b)