Research Article
Renin-Angiotensin System Gene Variants and Type 2 Diabetes Mellitus: Influence of Angiotensinogen
Table 1
Demographic and clinical data of participants.
| | Characteristics | (%) or mean ± SD | value | | Control () | DM () |
| | Gender | | | 0.824a | | Male | 108 (40) | 120 (41) | | | Female | 159 (60) | 170 (59) | | | Age | 57.0 ± 6.9 | 57.4 ± 6.2 | 0.618 | | BMI (kg/m2) | 26.9 ± 4.9 | 27.3 ± 4.6 | 0.317b | | Waist circumference (cm) | 86.3 ± 12.7 | 91.8 ± 11.9 | <0.000b | | Waist-to-hip ratio | 0.87 ± 0.1 | 0.90 ± 0.1 | <0.0001 | | Systolic blood pressure (mmHg) | 131.7 ± 15.5 | 133.7 ± 15.8 | 0.058 | | Diastolic blood pressure (mmHg) | 78.8 ± 10.3 | 77.8 ± 8.5 | 0.650 | | Fasting blood glucose (mmol/L) | 5.3 ± 0.7 | 8.4 ± 3.1 | <0.0001 | | HbA1c (%) (mmol/mol) | 5.5 ± 0.5 (36 ± 6) | 8.8 ± 1.9 (73 ± 21) | <0.0001 | | Serum urea (mmol/L) | 5.5 ± 7.8 | 5.3 ± 1.8 | <0.0001 | | Serum creatinine (mmol/L) | 76.9 ± 22.6 | 86.3 ± 25.3 | <0.0001 | | Glomerular filtration rate (mL/min/1.7 m2) | 85.4 ± 25.1 | 77.4 ± 23.3 | 0.988b | | Triglyceride (mmol/L) | 1.8 ± 5.2 | 1.8 ± 0.9 | <0.0001 | | Total cholesterol (mmol/L) | 5.2 ± 3.8 | 4.8 ± 3.2 | <0.0001 | | HDL cholesterol (mmol/L) | 1.9 ± 8.2 | 1.6 ± 5.9 | <0.0001 | | LDL cholesterol (mmol/L) | 3.0 ± 0.9 | 2.6 ± 1.0 | <0.0001 |
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values were obtained using Pearson’s test, b values were obtained using independent -test, and other comparisons used Mann-Whitney test.
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